Description

3-(3-Chloro-5-Fluorophenyl)-4'-Cyanopropiophenone CAS NO 898750-28-2 is a high-value, multi-functional organic intermediate featuring a unique halogenated and nitrile-substituted aromatic structure. This compound is critical for its role as a versatile building block in advanced organic synthesis, enabling the construction of complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its halogenated phenyl ring for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes, including cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic materials, such as liquid crystals or organic semiconductors, due to its rigid, conjugated backbone.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-4'-Cyanopropiophenone
CAS No.	898750-28-2
Molecular Formula	C16H11ClFNO
Molecular Weight	287.72 g/mol
Synonyms	1-[4-Cyanophenyl]-3-(3-chloro-5-fluorophenyl)propan-1-one; 3-(3-Chloro-5-fluorophenyl)-1-(4-cyanophenyl)propan-1-one; 4'-Cyano-3'-(3-chloro-5-fluorophenyl)propiophenone; Propiophenone, 3-(3-chloro-5-fluorophenyl)-4'-cyano-; 898750-28-2; CAS 898750-28-2
EINECS	Contact for details

Quality Control

Our production of 3-(3-Chloro-5-Fluorophenyl)-4'-Cyanopropiophenone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We operate under a cGMP-compliant quality system suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.