Description

3-(3-Chloro-5-Fluorophenyl)-4'-Methoxypropiophenone CAS NO 898750-19-1 is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its precise molecular architecture enables targeted drug development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Used in academic and industrial R&D for creating specialized polymers and liquid crystals with unique optical or electronic properties.
• Chemical Biology Probes: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-4'-Methoxypropiophenone
CAS No.	898750-19-1
Molecular Formula	C16H14ClFO2
Molecular Weight	292.73 g/mol
Synonyms	1-[4-Methoxyphenyl]-3-(3-chloro-5-fluorophenyl)propan-1-one; 4'-Methoxy-3-(3-chloro-5-fluorophenyl)propiophenone; 3-(3-Chloro-5-fluorophenyl)-1-(4-methoxyphenyl)propan-1-one; Propiophenone, 3-(3-chloro-5-fluorophenyl)-4'-methoxy-; 898750-19-1; 3-(3-Chloro-5-fluorophenyl)-4'-methoxypropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)-4'-Methoxypropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.