Description

3-(3-Chloro-5-Fluorophenyl)-3'-Methoxypropiophenone is a high-purity, advanced pharmaceutical intermediate with a distinct molecular structure. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific halogenated aromatic system serves as a key building block. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging its halogenated phenyl group for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in scale-up and pilot plant studies for the commercial manufacturing of target APIs.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals for client projects.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)-3'-Methoxypropiophenone
CAS No.	898750-16-8
Molecular Formula	C16H14ClFO2
Molecular Weight	292.73 g/mol
Synonyms	1-(3-Chloro-5-fluorophenyl)-3-(3-methoxyphenyl)propan-1-one; 3'-Methoxy-3-(3-chloro-5-fluorophenyl)propiophenone; Propiophenone, 3-(3-chloro-5-fluorophenyl)-3'-methoxy-; 898750-16-8; 3-(3-Chloro-5-fluorophenyl)-3'-methoxypropiophenone; 3-(3-Chloro-5-fluorophenyl)-3-methoxypropiophenone
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)-3'-Methoxypropiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.