Description

2',6'-Dichloro-3-(4-Trifluoromethylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and trifluoromethylated aromatic structure. This compound matters for its critical role in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and inflammatory pathways. Pharmaceutical R&D and manufacturing companies need this precise chemical building block to develop new drug candidates and ensure scalable, reproducible synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for CNS and anti-inflammatory drugs.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, where its aromatic and halogenated structure imparts specific electronic properties.
• Organic Synthesis: Employed in cross-coupling reactions and as a substrate for further functionalization in medicinal chemistry research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	2',6'-Dichloro-3-(4-Trifluoromethylphenyl)Propiophenone
CAS No.	898749-92-3
Molecular Formula	C16H11Cl2F3O
Molecular Weight	347.16 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-[4-(trifluoromethyl)phenyl]propan-1-one; 3-(4-Trifluoromethylphenyl)-2',6'-dichloropropiophenone; 2,6-Dichloro-3-(4-trifluoromethylphenyl)propiophenone; 898749-92-3; Propiophenone, 2',6'-dichloro-3-(4-(trifluoromethyl)phenyl)-; 1-(2,6-Dichlorophenyl)-3-(4-(trifluoromethyl)phenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-3-(4-Trifluoromethylphenyl)Propiophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture exposure. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.