Description

2',6'-Dichloro-3-(3-Trifluoromethylphenyl)Propiophenone is a high-value, multi-functional organic intermediate characterized by its distinct dichloro and trifluoromethylphenyl substituents. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and fluorinated motifs into target structures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and liquid crystals with specific optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2',6'-Dichloro-3-(3-Trifluoromethylphenyl)Propiophenone
CAS No.	898749-89-8
Molecular Formula	C16H11Cl2F3O
Molecular Weight	347.16 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-[3-(trifluoromethyl)phenyl]propan-1-one; 3-(3-Trifluoromethylphenyl)-2',6'-dichloropropiophenone; 2,6-Dichloro-3'-(trifluoromethyl)propiophenone; α,2,6-Trichloro-3'-(trifluoromethyl)propiophenone (related isomer); 898749-89-8; Propiophenone, 2',6'-dichloro-3-(3-trifluoromethylphenyl)-
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-3-(3-Trifluoromethylphenyl)Propiophenone is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.