Description

2',6'-Dichloro-3-(2-Trifluoromethylphenyl)Propiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct halogenated and trifluoromethylated aromatic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Serves as a precursor for developing advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Research & Development: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science: Potential intermediate for creating specialty polymers and liquid crystals due to its rigid, halogenated aromatic core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	2',6'-Dichloro-3-(2-Trifluoromethylphenyl)Propiophenone
CAS No.	898749-86-5
Molecular Formula	C16H11Cl2F3O
Molecular Weight	347.16 g/mol
Synonyms	1-(2,6-Dichlorophenyl)-3-[2-(trifluoromethyl)phenyl]propan-1-one; 3-(2-Trifluoromethylphenyl)-1-(2,6-dichlorophenyl)propan-1-one; 2,6-Dichloro-3'-(trifluoromethyl)propiophenone; 898749-86-5; Propiophenone, 2',6'-dichloro-3-(2-trifluoromethylphenyl)-; 1-Propanone, 1-(2,6-dichlorophenyl)-3-[2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-3-(2-Trifluoromethylphenyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment supports applications requiring high standards, including cGMP synthesis for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.