Description

3'-(3-Pyrrolinomethyl)-3,4,5-Trifluorobenzophenone is a high-value fluorinated aromatic ketone derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its molecular structure, featuring a trifluoromethylbenzophenone core linked to a pyrrolidine moiety, makes it indispensable for constructing complex molecules with enhanced bioavailability and metabolic stability. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals for electronic and optical applications.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	3'-(3-Pyrrolinomethyl)-3,4,5-Trifluorobenzophenone
CAS No.	898749-64-9
Molecular Formula	C18H15F3N1O1
Molecular Weight	318.32 g/mol
Synonyms	3,4,5-Trifluoro-3'-(pyrrolidin-3-ylmethyl)benzophenone; 1-[3-(3,4,5-Trifluorobenzoyl)benzyl]pyrrolidine; 3'-(3-Pyrrolidinylmethyl)-3,4,5-trifluorobenzophenone; (3,4,5-Trifluorophenyl)[3-[(3-pyrrolidinyl)methyl]phenyl]methanone; 898749-64-9; 3-(3-Pyrrolidinylmethyl)-3',4',5'-trifluorobenzophenone
EINECS	Contact for details

Quality Control

Our production of 3'-(3-Pyrrolinomethyl)-3,4,5-Trifluorobenzophenone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.