Description

2,4-Difluoro-3'-(3-Pyrrolinomethyl) Benzophenone is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzophenone core functionalized with fluorine and pyrrolidine groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those targeting protein kinases and G-protein-coupled receptors (GPCRs).
• Organic Light-Emitting Diode (OLED) Material Research: Serves as a precursor or core structure for developing electron-transport or host materials in OLED devices due to its conjugated benzophenone system.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides and fungicides, where the difluoro and benzophenone motifs can contribute to biological activity and photostability.
• Ligand and Catalyst Development: The pyrrolinomethyl group can act as a chelating unit, making it useful for constructing novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and R&D Laboratories: Employed in fundamental organic chemistry research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	2,4-Difluoro-3'-(3-Pyrrolinomethyl) Benzophenone
CAS No.	898749-58-1
Molecular Formula	C18H17F2NO
Molecular Weight	301.33 g/mol
Synonyms	2,4-Difluoro-3'-(pyrrolidin-3-ylmethyl)benzophenone; 1-[3-[(2,4-Difluorophenyl)carbonyl]phenyl]-3-pyrrolidinemethanol; 3'-(3-Pyrrolidinylmethyl)-2,4-difluorobenzophenone; (3-((2,4-Difluorobenzoyl)phenyl)methyl)pyrrolidine; Benzophenone, 2,4-difluoro-3'-(3-pyrrolidinylmethyl)-
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-3'-(3-Pyrrolinomethyl) Benzophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for demanding research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.