Description

3-Amino-3-(Tetrahydro-Thiopyran-4-Yl)-Propionic Acid is a specialized non-proteinogenic amino acid derivative featuring a unique thiopyran ring structure. This compound is of significant interest in pharmaceutical research and development, particularly as a key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and fine chemical manufacturers engaged in the development of peptidomimetics, enzyme inhibitors, and other bioactive molecules where the incorporation of a constrained, sulfur-containing heterocycle is desired.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and synthesis of novel drug candidates, particularly in neurological and metabolic disorder research.
• Peptidomimetic Chemistry: Used to introduce conformational constraints and modify the pharmacokinetic properties of peptide-based therapeutics.
• Chemical Biology Probe Development: Serves as a building block for creating molecular probes to study enzyme function and protein-protein interactions.
• Ligand Synthesis for Catalysis: Potential precursor for chiral ligands used in asymmetric synthesis and transition metal catalysis.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new chemical entities with potential biological activity.

Basic Information

Product Name	3-Amino-3-(Tetrahydro-Thiopyran-4-Yl)-Propionic Acid
CAS No.	898404-97-2
Molecular Formula	C8H15NO2S
Molecular Weight	189.27 g/mol
Synonyms	3-Amino-3-(tetrahydro-2H-thiopyran-4-yl)propanoic acid; 3-Amino-3-(tetrahydro-4H-thiopyran-4-yl)propionic acid; 3-Amino-3-(thiacyclohexan-4-yl)propionic acid; 4-(2-Carboxyethyl)thiomorpholine-3-carboxylic acid (tautomer); β-Amino-β-(tetrahydro-4-pyranthio)propionic acid; (R/S)-3-Amino-3-(tetrahydro-2H-thiopyran-4-yl)propanoic acid; 898404-97-2 (CAS); ATTPA
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(Tetrahydro-Thiopyran-4-Yl)-Propionic Acid is produced under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity suitable for research applications. Standard quality control includes identification, assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity (if applicable), and residual solvent levels is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	Contact for details
Loss on Drying	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.