Description

1-Methyl-1H-Indole-4-Boronic Acid, Pinacol Ester 97% is a high-purity, protected boronic acid derivative, also known as 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole. This compound is a critical Suzuki-Miyaura cross-coupling reagent, valued for its stability and reactivity in forming carbon-carbon bonds. It is essential for researchers and manufacturers in pharmaceutical development and advanced material science who require reliable, high-quality building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for indole-based drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with complex heterocyclic structures.
• Material Science: Serves as a precursor in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological systems.
• Academic & Contract Research: A vital reagent for methodological development in organic chemistry and catalysis research within university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex fragrance molecules, dyes, and other specialty chemicals.

Basic Information

Item	Details
Product Name	1-Methyl-1H-Indole-4-Boronic Acid, Pinacol Ester 97%
CAS No.	898289-06-0
Molecular Formula	C15H20BNO2
Molecular Weight	257.14 g/mol
Synonyms	1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 1-Methyl-1H-indole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-indole; 1-Methylindole-4-boronic acid pinacol ester; 898289-06-0; B-(1-Methyl-1H-indol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Indole-4-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.