Description

2-Hydroxyl-1-Naphthaleneboronicacid is a specialized naphthalene-based boronic acid derivative, a key building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions and other catalytic transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where it is used to construct complex molecular architectures for active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a key boronic acid reagent for forming carbon-carbon bonds in the production of complex biaryl structures.
• Advanced Material Synthesis: Used in the research and development of organic electronic materials, such as OLEDs and organic semiconductors.
• Agrochemical Research: Employed as an intermediate in the synthesis of new-generation pesticides and herbicides.
• Ligand and Catalyst Development: Utilized to create novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Acts as a precursor for developing molecular probes and sensors for biochemical research.

Basic Information

Item	Details
Product Name	2-Hydroxyl-1-Naphthaleneboronicacid
CAS No.	898257-48-2
Molecular Formula	C₁₀H₉BO₃
Molecular Weight	188.00 g/mol
Synonyms	2-Hydroxy-1-naphthaleneboronic acid; 2-Hydroxynaphthalene-1-boronic acid; 1-Borono-2-hydroxynaphthalene; 2-Hydroxy-1-naphthylboronic acid; (2-Hydroxynaphthalen-1-yl)boronic acid; 1-Naphthaleneboronic acid, 2-hydroxy-; 2-Hydroxy-1-naphthaleneboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 2-Hydroxyl-1-Naphthaleneboronicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.