Description

6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-1-One is a high-purity fluorinated tetralone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly influences the electronic and steric properties of downstream molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients where fluorination is a key design strategy.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, especially in central nervous system (CNS) and oncology research where fluorinated analogs are prevalent.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging fluorine's ability to enhance bioavailability and metabolic stability.
• Material Science Research: Serves as a precursor for fluorinated organic electronic materials, such as semiconductors or liquid crystals.
• Chemical Biology Probes: Utilized in creating fluorinated probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-1-One
CAS No.	895534-38-0
Molecular Formula	C₁₀H₈F₂O
Molecular Weight	182.17 g/mol
Synonyms	6,8-Difluoro-3,4-dihydronaphthalen-1(2H)-one; 6,8-Difluoro-α-tetralone; 1-Tetralone, 6,8-difluoro-1,2,3,4-tetrahydro-; 6,8-Difluoro-1-tetralone; 6,8-Difluorotetralone
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Each batch of 6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-1-One is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability, meeting the exacting requirements of global pharmaceutical and R&D customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.