Description

3-Amino-4-Methoxyphenylboronic Acid Hydrochloride is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the aromatic amine provides a handle for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, resins, and organic electronic materials.
• Ligand for Catalysis: Can be utilized to develop novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functionality makes it a versatile partner for constructing biaryl and heterobiaryl structures, a cornerstone reaction in medicinal chemistry.

Basic Information

Product Name	3-Amino-4-Methoxyphenylboronic Acid Hydrochloride
CAS No.	895525-75-4
Molecular Formula	C7H11BClNO3
Molecular Weight	203.43 g/mol
Synonyms	(3-Amino-4-methoxyphenyl)boronic acid hydrochloride; 3-Amino-4-methoxybenzeneboronic acid HCl; 4-Methoxy-3-aminophenylboronic acid hydrochloride; B-(3-Amino-4-methoxyphenyl)boronic acid hydrochloride; 895525-75-4; Boronic acid, B-(3-amino-4-methoxyphenyl)-, hydrochloride; 3-Amino-4-methoxy-phenylboronic acid hydrochloride salt
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-4-Methoxyphenylboronic Acid HCl is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.