Description

3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Ethyl Ester is a high-purity organic intermediate characterized by its β-keto ester functionality and a trifluoromethylphenyl substituent. This compound is a critical building block in modern synthetic organic chemistry, valued for its versatility in constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl moiety often contributes to efficacy.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for methodological studies, including cross-coupling reactions and the synthesis of heterocycles.
• Ligand and Catalyst Preparation: Utilized as a starting material for synthesizing novel ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Ethyl Ester
CAS No.	894802-88-1
Molecular Formula	C13H13F3O3
Molecular Weight	274.24 g/mol
Synonyms	Ethyl 3-oxo-4-[3-(trifluoromethyl)phenyl]butanoate; Ethyl 4-(3-Trifluoromethylphenyl)-3-oxobutyrate; 4-(3-Trifluoromethylphenyl)-3-oxobutanoic Acid Ethyl Ester; 3-Oxo-4-(m-trifluoromethylphenyl)butyric Acid Ethyl Ester; 3-(3-Trifluoromethylphenyl)-3-oxopropionic Acid Ethyl Ester; β-Keto Ester of 3-Trifluoromethylphenylacetic Acid; TFMP-β-ketoester
EINECS	Contact for details

Quality Control

Our 3-Oxo-4-(3-Trifluoromethyl-Phenyl)-Butyric Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.