Description

Methyl 4-Amino-2-(Trifluoromethyl)Benzoate is a high-value fluorinated aromatic building block, essential for synthesizing advanced molecules with enhanced biological activity and physicochemical properties. Its core value lies in the strategic combination of an amino group and a trifluoromethyl group on a benzoate ester scaffold, enabling precise modifications in drug discovery and material science. This compound is critically needed by R&D and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, enhancing charge transport and thermal stability.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: The amino and ester functionalities make it a versatile substrate for palladium-catalyzed and other metal-mediated coupling reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke chemical synthesis and scale-up projects.

Basic Information

Product Name	Methyl 4-Amino-2-(Trifluoromethyl)Benzoate
CAS No.	894796-87-3
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	Methyl 4-Amino-2-(trifluoromethyl)benzoate; Benzoic acid, 4-amino-2-(trifluoromethyl)-, methyl ester; 4-Amino-2-(trifluoromethyl)benzoic acid methyl ester; Methyl 4-amino-α,α,α-trifluoro-o-toluate; 2-(Trifluoromethyl)-4-aminobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-2-(Trifluoromethyl)Benzoate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.