Description

3-(3,4-Difluorophenyl)Prop-2-Yn-1-Ol is a high-purity fluorinated alkyne building block, a key intermediate in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through robust coupling reactions like Sonogashira and Click chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for candidates targeting central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, especially in kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing advanced herbicides and fungicides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers and advanced functional materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry: A valuable probe and building block in medicinal chemistry for modulating lipophilicity, metabolic stability, and bioavailability.
• Chemical Biology: Used in bioconjugation and probe development for studying biological systems.

Basic Information

Product Name	3-(3,4-Difluorophenyl)Prop-2-Yn-1-Ol
CAS No.	893747-16-5
Molecular Formula	C9H6F2O
Molecular Weight	168.14 g/mol
Synonyms	3-(3,4-Difluorophenyl)prop-2-yn-1-ol; 3,4-Difluorophenyl propargyl alcohol; 1-(3,4-Difluorophenyl)-2-propyn-1-ol; 2-Propyn-1-ol, 3-(3,4-difluorophenyl)-; 3-(3,4-Difluorophenyl)-2-propyn-1-ol; 3,4-Difluoro-propargyl alcohol; Propargyl alcohol, 3,4-difluoro-
EINECS	Contact for details

Quality Control

Our 3-(3,4-Difluorophenyl)Prop-2-Yn-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.