Description

B-(2-Cyclopropyl-5-Pyrimidinyl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Enables the efficient construction of biaryl and heterobiaryl structures prevalent in many functional molecules through palladium-catalyzed cross-coupling reactions.
• Library Synthesis: Employed in medicinal chemistry for the rapid parallel synthesis of diverse compound libraries to accelerate hit-finding and lead optimization.
• Catalyst & Ligand Development: Used to synthesize novel bidentate or tridentate ligands for transition metal catalysis.

Basic Information

Product Name	B-(2-Cyclopropyl-5-Pyrimidinyl)Boronic Acid
CAS No.	893567-15-2
Molecular Formula	C7H9BN2O2
Molecular Weight	163.97 g/mol
Synonyms	(2-Cyclopropylpyrimidin-5-yl)boronic acid; 2-Cyclopropyl-5-pyrimidineboronic acid; 5-Borono-2-cyclopropylpyrimidine; B-(2-Cyclopropyl-5-pyrimidinyl)boronic acid; 2-Cyclopropylpyrimidine-5-boronic acid; (2-Cyclopropyl-5-pyrimidinyl)boronic Acid; 893567-15-2
EINECS	Contact for details

Quality Control

Our B-(2-Cyclopropyl-5-Pyrimidinyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee reproducible performance in your critical coupling reactions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage and when dispensing to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.