Description

1,3,2-Dioxaborolane, 2-(2-Chloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl- is a high-purity, organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient and selective cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing biaryl motifs.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide candidates through palladium-catalyzed cross-coupling.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the synthesis of boron-containing molecules for bioimaging and drug discovery.
• Scale-up Process Chemistry: Suitable for process optimization and pilot-scale manufacturing of target molecules.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-(2-Chloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl-
CAS No.	892845-64-6
Molecular Formula	C12H15BClFO2
Molecular Weight	255.51 g/mol
Synonyms	2-(2-Chloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-Chloro-4-fluorophenyl)boronic acid pinacol ester; 2-Chloro-4-fluorophenylboronic acid pinacol ester; 4-Fluoro-2-chlorophenylboronic acid pinacol ester; Pinacol (2-chloro-4-fluorophenyl)boronate; (2-Chloro-4-fluorophenyl)BPin; CAS 892845-64-6
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 2-(2-Chloro-4-Fluorophenyl)-4,4,5,5-Tetramethyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and GC analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.