Description

2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value, multifunctional chemical building block that combines a carboxylic acid group with a protected boronic ester functionality. This compound is essential for enabling complex organic synthesis, particularly through cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and agrochemical development. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used to construct complex molecules for novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological processes and drug discovery.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	890839-31-3
Molecular Formula	C13H16BClO4
Molecular Weight	282.53 g/mol
Synonyms	2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-chlorobenzoic Acid; 2-Chloro-4-(pinacolatoboryl)benzoic Acid; 2-Chloro-4-borono-benzoic acid pinacol ester; Benzoic acid, 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 890839-31-3; 2-Chloro-4-(pinacolboronato)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.