Description

2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aromatic boronate functionalities.
• Material Science: Building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical spaces via cross-coupling.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex flavors, fragrances, and specialty chemicals.

Basic Information

Item	Details
Product Name	2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	890839-25-5
Molecular Formula	C16H23BO4
Molecular Weight	290.17 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isopropylbenzoic acid; 2-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; Benzoic acid, 2-(1-methylethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Isopropyl-4-(pinacolatoboryl)benzoic acid; 4-(Pinacolatoboryl)-2-isopropylbenzoic acid; 2-Isopropyl-4-borono-benzoic acid pinacol ester; 890839-25-5; 2-Isopropyl-4-(pinacol boronate)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Isopropyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality documentation to meet specific customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.