Description

Methyl 2-Methyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanoate is a high-purity, synthetically valuable organoboron building block. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura coupling, due to its stable boronate ester group. It is primarily used by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a monomer or building block for creating advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and bioconjugates for studying biological processes and diagnostics.
• Academic & Industrial R&D: A fundamental reagent for methodology development in organic chemistry and scale-up process research.

Basic Information

Product Name	Methyl 2-Methyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanoate
CAS No.	890839-10-8
Molecular Formula	C₁₇H₂₅BO₄
Molecular Weight	304.19 g/mol
Synonyms	2-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propanoic acid methyl ester; Methyl 2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-2-methylpropanoate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid, α,α-dimethyl-, methyl ester; Pinacol (4-(1-Methoxy-2-methyl-1-oxopropan-2-yl)phenyl)boronate; 890839-10-8
EINECS	Contact for details

Quality Control

Our Methyl 2-Methyl-2-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.