Description

1-(4-Fluoro-Phenyl)-1H-Pyrazole-4-Carbaldehyde is a versatile and high-purity fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a reactive aldehyde functional group attached to a fluorinated aromatic pyrazole scaffold, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require reliable, high-quality intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorinated pyrazole structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorescent markers.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis and Scale-Up: Provides a reliable, specification-controlled starting point for contract research organizations (CROs) and custom synthesis partners.

Basic Information

Product Name	1-(4-Fluoro-Phenyl)-1H-Pyrazole-4-Carbaldehyde
CAS No.	890652-03-6
Molecular Formula	C10H7FN2O
Molecular Weight	190.18 g/mol
Synonyms	1-(4-Fluorophenyl)-1H-pyrazole-4-carboxaldehyde; 4-Fluoro-1H-pyrazole-1-benzaldehyde; 1H-Pyrazole-4-carboxaldehyde, 1-(4-fluorophenyl)-; 4-Fluorophenylpyrazole-4-carbaldehyde; 890652-03-6; 1-(p-Fluorophenyl)-1H-pyrazole-4-carbaldehyde; 1-(4-Fluorophenyl)-4-formylpyrazole
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Fluoro-Phenyl)-1H-Pyrazole-4-Carbaldehyde is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of related substances. A comprehensive Certificate of Analysis (COA) documenting results for assay, identity (IR, NMR), and impurity profile (HPLC) is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.