Description

3-Acetoxy-3',4'-Difluorobenzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise molecular structure, which is engineered to introduce key fluorinated aromatic motifs into target molecules, enhancing their metabolic stability and binding affinity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel active ingredients for life sciences applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of modern fluorinated pesticides and herbicides, where the difluoroacetoxy group can improve efficacy and environmental profile.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique optical or thermal properties.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic display technologies.
• Organic Synthesis & Catalysis: A versatile reagent for introducing fluorinated benzoyl groups in complex organic molecule construction.
• Academic & Contract Research: A valuable tool for medicinal chemistry programs in universities and contract research organizations (CROs) exploring structure-activity relationships (SAR).

Basic Information

Product Name	3-Acetoxy-3',4'-Difluorobenzophenone
CAS No.	890100-20-6
Molecular Formula	C15H10F2O3
Molecular Weight	276.24 g/mol
Synonyms	3-(Acetyloxy)-3',4'-difluorobenzophenone; 1-[3-(Acetyloxy)phenyl]-2,3-difluorophenylmethanone; 3',4'-Difluoro-3-hydroxybenzophenone acetate; 3-Acetoxy-3',4'-difluorobenzophenone; (3',4'-Difluorophenyl)(3-acetoxyphenyl)methanone; 3-Acetyloxy-3',4'-difluorobenzophenone; Benzophenone, 3-(acetyloxy)-3',4'-difluoro-
EINECS	Contact for details

Quality Control

Our 3-Acetoxy-3',4'-Difluorobenzophenone is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistent batch-to-batch reproducibility for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize moisture exposure. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.