Description

4-Acetoxy-3'-Iodobenzophenone is a high-purity iodinated benzophenone derivative, serving as a versatile and critical synthetic intermediate. Its value lies in its unique molecular structure, which incorporates both a photoreactive benzophenone core and a protected phenolic group, making it essential for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of advanced materials, photoaffinity labeling probes, and novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Photoaffinity Labeling Probe Synthesis: Used to create probes for studying protein-ligand interactions and biological target identification due to the benzophenone moiety's ability to form covalent bonds upon UV irradiation.
• Advanced Material Research: Serves as a precursor in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular tools for activity-based protein profiling and other chemoproteomic applications.
• Organic Synthesis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and for introducing the iodophenyl group into complex molecular architectures.

Basic Information

Product Name	4-Acetoxy-3'-Iodobenzophenone
CAS No.	890099-50-0
Molecular Formula	C15H11IO3
Molecular Weight	366.15 g/mol
Synonyms	3'-Iodo-4-acetoxybenzophenone; 4-Acetyloxy-3'-iodobenzophenone; [4-(Acetyloxy)phenyl](3-iodophenyl)methanone; 4-Acetoxy-3'-iodo-benzophenone; (3-Iodophenyl)(4-acetoxyphenyl)methanone
EINECS	Contact for details

Quality Control

Every batch of 4-Acetoxy-3'-Iodobenzophenone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.