Description

3-Acetoxy-3',4',5'-Trifluorobenzophenone is a high-purity fluorinated benzophenone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular structure, which incorporates both a photoreactive benzophenone core and strategically placed fluorine and acetoxy groups, enabling precise modifications in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require sophisticated building blocks for developing new active ingredients, particularly for applications demanding enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the trifluoromethyl and benzophenone motifs contribute to efficacy and environmental profile.
• Photoinitiator & Polymer Chemistry: Acts as a specialized photoinitiator or cross-linking agent in the production of advanced polymers, coatings, and UV-curable resins.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors or light-emitting diodes (OLEDs), due to its electron-accepting properties.
• Liquid Crystal & Display Technology: Serves as a precursor for fluorinated compounds used in liquid crystal mixtures for high-performance displays.
• Chemical Biology & Proteomics: Utilized as a photoreactive probe for studying protein-protein interactions and protein labeling via benzophenone-mediated photochemistry.

Basic Information

Product Name	3-Acetoxy-3',4',5'-Trifluorobenzophenone
CAS No.	890099-23-7
Molecular Formula	C15H9F3O3
Molecular Weight	294.23 g/mol
Synonyms	3-(Acetyloxy)-3',4',5'-trifluorobenzophenone; 3',4',5'-Trifluoro-3-hydroxybenzophenone acetate; 1-[3-(3,4,5-Trifluorobenzoyl)phenyl] ethyl acetate; 3-Acetoxy-3',4',5'-trifluorobenzophenone; Benzophenone, 3-(acetyloxy)-3',4',5'-trifluoro-; (3-Benzoyl-3',4',5'-trifluorophenyl) acetate
EINECS	Contact for details

Quality Control

Our 3-Acetoxy-3',4',5'-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications in cGMP environments, and we can tailor purity grades to meet specific project requirements, from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be kept under inert conditions if long-term storage is required. Keep away from strong bases and incompatible materials. Ensure containers are kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.