Description

2-Acetoxy-2',3',4',5',6'-Pentafluorobenzophenone is a specialized fluorinated aromatic ketone derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic incorporation of fluorine atoms and an acetoxy group, which are pivotal for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex scaffolds in drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the pentafluorophenyl group enhances biological activity and environmental persistence.
• Material Science Precursor: Employed in the creation of specialty polymers and liquid crystals, where fluorinated aromatic units impart unique thermal stability and optical properties.
• Organic Synthesis Reagent: Functions as a versatile electrophile or protecting group synthon in complex multi-step organic transformations, including cross-coupling reactions.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	2-Acetoxy-2',3',4',5',6'-Pentafluorobenzophenone
CAS No.	890099-21-5
Molecular Formula	C15H7F5O3
Molecular Weight	330.21 g/mol
Synonyms	2-(Acetyloxy)-2',3',4',5',6'-pentafluorobenzophenone; Pentafluorobenzoylphenyl Acetate; 2-Acetoxy-2,3,4,5,6-pentafluorobenzophenone; Benzophenone, 2-(acetyloxy)-2',3',4',5',6'-pentafluoro-; 2'-Acetoxy-2,3,4,5,6-pentafluorobenzophenone; α-Acetoxypentafluorobenzophenone; PFB-OAc Ketone
EINECS	Contact for details

Quality Control

Our 2-Acetoxy-2',3',4',5',6'-Pentafluorobenzophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.