Description

2-Acetoxy-3',4',5'-Trifluorobenzophenone is a high-purity, specialized fluorinated benzophenone derivative. This compound serves as a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate a trifluoromethylphenyl moiety with an acetoxy-protected ketone functionality.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for electronic display applications.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with unique thermal and chemical resistance.
• Organic Synthesis Research: A versatile reagent for academic and industrial research involving Friedel-Crafts acylation and subsequent functional group transformations.
• Photoinitiator Precursor: Used in the development of next-generation photoinitiators for UV-curable coatings and inks.

Basic Information

Product Name	2-Acetoxy-3',4',5'-Trifluorobenzophenone
CAS No.	890099-18-0
Molecular Formula	C15H9F3O3
Molecular Weight	294.23 g/mol
Synonyms	2-(Acetyloxy)-3',4',5'-trifluorobenzophenone; 2-Acetoxy-3,4,5-trifluorobenzophenone; [3,4,5-Trifluorophenyl](2-acetoxyphenyl)methanone; 2'-Acetoxy-3,4,5-trifluorobenzophenone; Benzophenone, 2-(acetyloxy)-3',4',5'-trifluoro-; 890099-18-0; 3',4',5'-Trifluoro-2-acetoxybenzophenone
EINECS	Contact for details

Quality Control

Our 2-Acetoxy-3',4',5'-Trifluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.