Description

2-Cyano-4'-Iodobenzophenone is a high-value, multi-functional organic building block characterized by its distinct benzophenone core functionalized with cyano and iodo substituents. This compound is essential for facilitating advanced synthetic transformations, particularly in the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for applications in medicinal chemistry, ligand synthesis, and as a precursor for functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and bioactive molecules, particularly those targeting kinase inhibition or acting as enzyme modulators.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators where its halogen and nitrile groups enable unique modes of action.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, charge-transport materials, and light-emitting layers in organic light-emitting diodes (OLEDs) and photovoltaic cells.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Heck) to form complex biaryl and conjugated systems.
• Ligand & Catalyst Synthesis: Utilized for constructing sophisticated chelating ligands for transition metal catalysts used in asymmetric synthesis and polymerization.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for developing molecular probes, photoaffinity labels, and tools for studying protein-ligand interactions.

Basic Information

Product Name	2-Cyano-4'-Iodobenzophenone
CAS No.	890098-79-0
Molecular Formula	C14H8INO
Molecular Weight	333.13 g/mol
Synonyms	4'-Iodo-2-cyanobenzophenone; (4-Iodophenyl)(2-cyanophenyl)methanone; 2-Cyanophenyl 4-iodophenyl ketone; Benzophenone, 2-cyano-4'-iodo-; 890098-79-0; 2-CN-4'-I-BP
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-4'-Iodobenzophenone is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and development applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and meet your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.