Description

3-Fluoro-3'-Iodobenzophenone is a high-value, multi-functional aromatic ketone building block. This compound is engineered for advanced synthesis, offering two distinct halogen handles for selective cross-coupling and functionalization reactions. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical sectors for creating novel active ingredients and complex molecular architectures. Its unique substitution pattern makes it a critical intermediate for constructing fluorinated and iodinated compounds with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those requiring fluorinated or iodinated aromatic systems for enhanced metabolic stability, bioavailability, or receptor binding.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine and iodine atoms can be leveraged to fine-tune biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or intermediate for synthesizing specialized polymers, liquid crystals, or organic electronic materials that benefit from halogenated aromatic units.
• Cross-Coupling Reactions: The iodine atom is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Sonogashira), while the fluorine can be used for further selective derivatization or as a stable bioisostere.
• Chemical Synthesis & Process Development: Employed in organic synthesis laboratories for method development and as a versatile scaffold for constructing complex, multi-substituted benzophenone derivatives.

Basic Information

Product Name	3-Fluoro-3'-Iodobenzophenone
CAS No.	890098-25-6
Molecular Formula	C13H8FIO
Molecular Weight	326.11 g/mol
Synonyms	3-Fluoro-3'-iodobenzophenone; (3-Fluorophenyl)(3-iodophenyl)methanone; 3'-Iodo-3-fluorobenzophenone; Methanone, (3-fluorophenyl)(3-iodophenyl)-; Benzophenone, 3-fluoro-3'-iodo-
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-3'-Iodobenzophenone is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.