Description

Methylenebis(4,1-Phenylene) Bis(Trifluoromethanesulfonate) is a high-value, specialty chemical building block featuring two highly reactive triflate ester groups. This compound is critical for advanced organic synthesis, enabling efficient cross-coupling reactions and the introduction of functional groups under mild conditions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and diarylmethane scaffolds via Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the introduction of specific aromatic systems is required.
• Ligand and Catalyst Development: Serves as a versatile building block for creating sophisticated phosphine, N-heterocyclic carbene (NHC), and other chelating ligands used in homogeneous catalysis.
• Polymer and Material Science: Employed in the synthesis of specialty monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: An essential reagent in academic and industrial R&D labs for methodological studies in organic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	Methylenebis(4,1-Phenylene) Bis(Trifluoromethanesulfonate)
CAS No.	889676-12-4
Molecular Formula	C₁₅H₁₀F₆O₆S₂
Molecular Weight	488.36 g/mol
Synonyms	4,4'-Bis(trifluoromethanesulfonyloxy)diphenylmethane; Bis(4-(trifluoromethanesulfonyloxy)phenyl)methane; 4,4'-Methylenebis(phenyl triflate); Bis(4-triflyloxyphenyl)methane; 4,4'-(Methanediyl)bis(phenyl trifluoromethanesulfonate); 1,1'-(Methylenedi-4,1-phenylene) bis(trifluoromethanesulfonate); Bis(4-trifluoromethanesulfonatophenyl)methane
EINECS	Contact for details

Quality Control

Our production of Methylenebis(4,1-Phenylene) Bis(Trifluoromethanesulfonate) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.