Description

6α,7α-Drospirenone CAS NO 889652-31-7 is a high-purity synthetic steroid compound, recognized as a key intermediate in the synthesis of modern pharmaceutical actives. Its primary commercial value lies in enabling the production of advanced steroidal APIs with precise stereochemistry and high biological activity. This compound is essential for pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) focused on developing and producing next-generation hormonal therapies and other specialized medicinal products.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of drospirenone and related progestin-based active pharmaceutical ingredients (APIs).
• Hormone Therapy Research: Used in the research and development of novel oral contraceptives and hormone replacement therapies (HRT).
• Steroid Chemistry: Serves as a versatile precursor in advanced organic synthesis for creating modified steroid structures with targeted properties.
• Reference Standard: Employed as an analytical reference standard in quality control laboratories for method development and impurity profiling.
• Process Development: Utilized in scale-up and optimization studies for commercial pharmaceutical manufacturing processes.

Basic Information

Product Name	6α,7α-Drospirenone
CAS No.	889652-31-7
Molecular Formula	C24H30O3
Molecular Weight	366.50 g/mol
Synonyms	6α,7α-Dihydrodrospirenone; (6α,7α)-6,7-Dihydro-15β,16β-methylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone; 6α,7α-Dihydro-15β,16β-methylen-3-oxo-17α-pregn-4-en-21,17-carbolacton; Drospirenone Dihydro Derivative; 6α,7α-Dihydrodrospirenon; Pregn-4-ene-21,17-carbolactone, 6,7-dihydro-15β,16β-methylene-3-oxo-17α-, (6α,7α)-
EINECS	Contact for details

Quality Control

Our 6α,7α-Drospirenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by Chiral HPLC)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.