Description

(2S,3S,4Ar,6R,8Ar)-2,3,4A,5,6,8A-Hexahydro-7-Iodo-2,3-Dimethoxy-2,3,6-Trimethyl-1,4-Benzodioxin-6-Ol CAS NO 888723-97-5 is a complex, stereochemically defined iodinated benzodioxin derivative. This compound is a valuable advanced pharmaceutical intermediate (API intermediate) and a crucial building block for synthetic organic chemistry research. It is primarily needed by pharmaceutical R&D teams and fine chemical synthesis specialists developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly in medicinal chemistry programs.
• Organic Synthesis Building Block: Used for constructing intricate molecular architectures in academic and industrial research laboratories.
• Methodology Development: Serves as a challenging substrate for developing new synthetic transformations and catalytic processes.
• Chemical Biology Probe: Potential use in developing molecular probes due to its unique iodinated and oxygenated structure.
• Asymmetric Synthesis: Utilized in stereoselective synthesis, leveraging its defined chiral centers to induce chirality in target molecules.

Basic Information

Product Name	(2S,3S,4Ar,6R,8Ar)-2,3,4A,5,6,8A-Hexahydro-7-Iodo-2,3-Dimethoxy-2,3,6-Trimethyl-1,4-Benzodioxin-6-Ol
CAS No.	888723-97-5
Molecular Formula	C₁₃H₂₁IO₅
Molecular Weight	384.21 g/mol
Synonyms	7-Iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxan-6-ol; (2S,3S,4aR,6R,8aR)-7-Iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxan-6-ol; Hexahydro-7-iodo-2,3-dimethoxy-2,3,6-trimethyl-1,4-benzodioxin-6-ol; CAS 888723-97-5; Iodinated Benzodioxin Derivative; Advanced Chiral Intermediate; Pharmaceutical Building Block 888723-97-5
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.