Description

(S)-1-Amino-1-(4-Fluorophenyl)-2-Methylpropan-2-Ol is a chiral amino alcohol building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring a stereogenic center and a fluorinated aromatic ring, makes it a versatile precursor for the development of active pharmaceutical ingredients (APIs) and other fine chemicals. Pharmaceutical research and development teams, particularly those working on central nervous system (CNS) agents, receptor modulators, and other fluorinated bioactive molecules, are the primary industrial users of this high-value intermediate.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, especially those targeting neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of novel, fluorinated pesticides and herbicides where the chiral center can influence biological activity and environmental fate.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the enantioselectivity of various chemical transformations.
• Fluorine Chemistry Studies: An important compound for research into the effects of fluorine substitution on the physicochemical and biological properties of organic molecules.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals beyond the pharmaceutical sector.

Basic Information

Product Name	(S)-1-Amino-1-(4-Fluorophenyl)-2-Methylpropan-2-Ol
CAS No.	888028-36-2
Molecular Formula	C10H14FNO
Molecular Weight	183.22 g/mol
Synonyms	(S)-1-Amino-1-(4-fluorophenyl)-2-methylpropan-2-ol; (S)-1-(4-Fluorophenyl)-2-methyl-2-aminopropan-1-ol; (S)-4-Fluoro-α-(1-amino-1-methylethyl)benzyl alcohol; (S)-1-(4-Fluorophenyl)-2-amino-2-methylpropan-1-ol; (S)-2-Amino-2-methyl-1-(4-fluorophenyl)propan-1-ol; (1S)-1-Amino-1-(4-fluorophenyl)-2-methylpropan-2-ol; (S)-FAMP (abbreviation)
EINECS	Contact for details

Quality Control

Our (S)-1-Amino-1-(4-Fluorophenyl)-2-Methylpropan-2-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.