Description

5-[2-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde is a high-value, multi-functional aromatic aldehyde building block. This compound is essential for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating chiral ligands, organocatalysts, and metal-organic frameworks (MOFs) used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the introduction of specific aromatic and fluorinated motifs is required.
• Chemical Biology Probes: Useful for designing fluorescent tags, photoaffinity labels, and other molecular probes for studying biological systems.

Basic Information

Product Name	5-[2-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde
CAS No.	887973-92-4
Molecular Formula	C13H8F3NO2
Molecular Weight	267.20 g/mol
Synonyms	3-Pyridinecarboxaldehyde, 5-[2-(trifluoromethoxy)phenyl]-; 5-(2-(Trifluoromethoxy)phenyl)nicotinaldehyde; 5-(2-Trifluoromethoxyphenyl)pyridine-3-carbaldehyde; 5-(2-(Trifluoromethoxy)phenyl)-3-pyridylcarboxaldehyde; 5-(2-Trifluoromethoxyphenyl)nicotinaldehyde; 5-(o-Trifluoromethoxyphenyl)nicotinaldehyde; 5-(2-Trifluoromethoxyphenyl)-3-formylpyridine
EINECS	Contact for details

Quality Control

Our 5-[2-(Trifluoromethoxy)Phenyl]-3-Pyridinecarbaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in cGMP and other regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.