Description

[4-(Difluoromethoxy)Benzyl]Hydrazine Hydrochloride is a high-purity, specialized organic intermediate of significant importance in modern synthetic chemistry. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the difluoromethoxy moiety for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a versatile starting material for creating specialized hydrazine-based ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and functional materials requiring specific benzyl-hydrazine linkages.
• Research & Development: Essential reagent in academic and industrial R&D labs for exploring new reaction pathways and heterocyclic compound libraries.

Basic Information

Item	Details
Product Name	[4-(Difluoromethoxy)Benzyl]Hydrazine Hydrochloride
CAS No.	887596-65-8
Molecular Formula	C8H10F2N2O·HCl
Molecular Weight	224.63 g/mol
Synonyms	1-[4-(Difluoromethoxy)phenyl]methanamine hydrochloride; 4-(Difluoromethoxy)benzylhydrazine hydrochloride; (4-(Difluoromethoxy)phenyl)methanamine hydrochloride; p-(Difluoromethoxy)benzylhydrazine HCl; α-Hydrazino-4-(difluoromethoxy)toluene hydrochloride; DFMBH-HCl; 4-DFMO-Bn-NHNH2·HCl
EINECS	Contact for details

Quality Control

Our [4-(Difluoromethoxy)Benzyl]Hydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.