Description

D(+)-A-Hydrazinohistidine Hydrochloride is a specialized chiral derivative of the amino acid histidine, modified with a hydrazine group. This high-purity biochemical is critical for advanced research and development in pharmaceutical chemistry and enzymology. It is primarily utilized by scientists and manufacturers in the life sciences sector for applications such as enzyme inhibition studies and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates and enzyme inhibitors.
• Biochemical Research: Used as a selective reagent in enzyme mechanism studies, particularly for investigating histidine-dependent enzymes.
• Proteomics & Peptide Synthesis: Acts as a modified amino acid derivative for the preparation of specialized peptides and affinity labels.
• Diagnostic Agent Development: Employed in research for developing novel diagnostic compounds and imaging agents.
• Academic & Industrial R&D: Essential for fundamental research in universities and corporate R&D labs focusing on medicinal chemistry and biochemistry.

Basic Information

Product Name	D(+)-A-Hydrazinohistidine Hydrochloride
CAS No.	1199-91-3
Molecular Formula	C6H12N5O2 • HCl
Molecular Weight	237.66 g/mol (Free base: 186.19)
Synonyms	D-α-Hydrazinohistidine Hydrochloride; (2S)-2-Hydrazinyl-3-(1H-imidazol-4-yl)propanoic Acid Hydrochloride; D-Histidine, α-hydrazino-, hydrochloride; L-Histidine, α-hydrazino-, hydrochloride (D-isomer); D-α-Hydrazino-1H-imidazole-4-propanoic Acid Hydrochloride; NSC 113943; D(+)-1H-Imidazole-4-propanoic acid, α-hydrazino-, monohydrochloride
EINECS	Contact for details

Quality Control

Our D(+)-A-Hydrazinohistidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.