Description

Cyclohexylmethyl-(4-Trifluoromethyl-Phenyl)-Amine is a specialized organic amine compound featuring a trifluoromethylphenyl group, which imparts unique electronic and steric properties. This compound matters as a high-value pharmaceutical intermediate and agrochemical building block, where its structural motifs are critical for developing active ingredients with enhanced metabolic stability and bioavailability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, crop protection, and advanced material sectors for synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a precursor for advanced herbicides and fungicides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for asymmetric catalysis and cross-coupling reactions.
• Material Science Research: Intermediate for synthesizing functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic and Industrial R&D: Utilized in research laboratories for method development and exploring new chemical entities.

Basic Information

Product Name	Cyclohexylmethyl-(4-Trifluoromethyl-Phenyl)-Amine
CAS No.	887590-21-8
Molecular Formula	C14H18F3N
Molecular Weight	257.30 g/mol
Synonyms	N-Cyclohexylmethyl-4-(trifluoromethyl)aniline; 4-(Trifluoromethyl)-N-(cyclohexylmethyl)aniline; 1-[(4-Trifluoromethylphenyl)amino]methylcyclohexane; N-[(4-Trifluoromethyl)phenyl]cyclohexanemethanamine; Cyclohexanemethanamine, N-[4-(trifluoromethyl)phenyl]-; α-(Cyclohexylmethylamino)-α,α,α-trifluoro-p-xylene
EINECS	Contact for details

Quality Control

Our Cyclohexylmethyl-(4-Trifluoromethyl-Phenyl)-Amine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.