Description

1-Boc-3-[2-(3-Bromo-Phenyl)-Ethylamino]-Azetidine is a high-purity, advanced pharmaceutical intermediate featuring a protected azetidine core, which is critical for modern drug discovery programs. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, enabling medicinal chemists to explore novel chemical space and develop new therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of small-molecule drugs, particularly those targeting central nervous system disorders and other areas requiring sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Protease Inhibitor Development: Serves as a precursor in the creation of inhibitors targeting specific enzymatic pathways.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1-Boc-3-[2-(3-Bromo-Phenyl)-Ethylamino]-Azetidine
CAS No.	887579-86-4
Molecular Formula	C16H23BrN2O2
Molecular Weight	355.27 g/mol
Synonyms	tert-Butyl 3-[2-(3-bromophenyl)ethylamino]azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-[2-(3-bromophenyl)ethylamino]azetidine; 3-[2-(3-Bromophenyl)ethylamino]azetidine-1-carboxylic acid tert-butyl ester; 1-Boc-3-[(2-(3-bromophenyl)ethyl)amino]azetidine; Azetidine, 3-[2-(3-bromophenyl)ethylamino]-1-[(1,1-dimethylethoxy)carbonyl]-; 887579-86-4
EINECS	Contact for details

Quality Control

Our 1-Boc-3-[2-(3-Bromo-Phenyl)-Ethylamino]-Azetidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with client requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.