Description

1-[4-(3-Trifluoromethoxy-Phenoxy)-Phenyl]-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethoxy and phenoxy functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high specificity and metabolic stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the trifluoromethoxy group for enhanced biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices due to its aromatic and fluorinated structure.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with unique thermal and chemical resistance properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating compound libraries for screening.

Basic Information

Product Name	1-[4-(3-Trifluoromethoxy-Phenoxy)-Phenyl]-Ethanone
CAS No.	887575-19-1
Molecular Formula	C15H11F3O3
Molecular Weight	296.24 g/mol
Synonyms	1-[4-(3-(Trifluoromethoxy)phenoxy)phenyl]ethanone; 4'-(3-Trifluoromethoxyphenoxy)acetophenone; 1-[4-[3-(Trifluoromethoxy)phenoxy]phenyl]ethan-1-one; Ethanone, 1-[4-[3-(trifluoromethoxy)phenoxy]phenyl]-; 3'-Trifluoromethoxy-4-phenoxyacetophenone; 4-(3-Trifluoromethoxyphenoxy)acetophenone; TFMPE Acetophenone Derivative
EINECS	Contact for details

Quality Control

Our 1-[4-(3-Trifluoromethoxy-Phenoxy)-Phenyl]-Ethanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.