Description

6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique indazole core structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly in oncology and inflammation research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the R&D of potential anti-cancer agents due to its indazole scaffold, which is prevalent in many investigational compounds.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Biochemical Research: Employed in the study of enzyme inhibition and cellular signaling pathways as a core structural motif.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Item	Details
Product Name	6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxaldehyde
CAS No.	887569-72-4
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	6-Chloro-4-hydroxy-1H-indazole-3-carbaldehyde; 6-Chloro-4-hydroxyindazole-3-carboxaldehyde; 3-Formyl-6-chloro-4-hydroxy-1H-indazole; 1H-Indazole-3-carboxaldehyde, 6-chloro-4-hydroxy-; 887569-72-4
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Hydroxy-3-(1H)Indazole Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.