Description

3-(4-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazole core enables the creation of molecules with targeted biological activity. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new products.

Application

• Pharmaceutical Intermediate: A key synthon for the research and production of novel drug candidates, particularly in therapeutic areas requiring heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its chlorophenyl-pyrazole structure.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in synthesizing specialized ligands, polymers, or functional materials with specific electronic or binding properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or ISO standards.

Basic Information

Product Name	3-(4-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid
CAS No.	887408-58-4
Molecular Formula	C10H7ClN2O2
Molecular Weight	222.63 g/mol
Synonyms	5-(4-Chlorophenyl)-1H-pyrazole-3-carboxylic acid; 1H-Pyrazole-3-carboxylic acid, 5-(4-chlorophenyl)-; 3-(p-Chlorophenyl)-1H-pyrazole-5-carboxylic acid; 4-Chloro-1H-pyrazole-5-carboxylic acid phenyl derivative; Pyrazole-5-carboxylic acid, 3-(4-chlorophenyl)-; 887408-58-4; 3-(4-Chlorophenyl)-1H-pyrazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenyl)-1H-Pyrazole-5-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production can be aligned with cGMP and ISO 9001 standards to meet the stringent requirements of pharmaceutical and advanced chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.