Description

1-(2,4-Dichloro-5-Fluoro-3-Nitrophenyl)Ethanone is a high-purity, multi-functional aromatic ketone building block of significant importance in advanced organic synthesis. Its unique halogenated nitroacetophenone structure makes it a critical intermediate for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluoroquinolone antibiotics and other active pharmaceutical ingredients (APIs) requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the dichloro-fluoro-nitro substitution pattern contributes to biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where nitro and halogen groups modify color and fastness properties.
• Chemical Research & Development: A versatile substrate for exploring novel organic reactions, such as nucleophilic aromatic substitution (SNAr) and cross-coupling reactions.

Basic Information

Product Name	1-(2,4-Dichloro-5-Fluoro-3-Nitrophenyl)Ethanone
CAS No.	887267-36-9
Molecular Formula	C8H4Cl2FNO3
Molecular Weight	252.03 g/mol
Synonyms	2',4'-Dichloro-5'-fluoro-3'-nitroacetophenone; 1-Acetyl-2,4-dichloro-5-fluoro-3-nitrobenzene; 2,4-Dichloro-5-fluoro-3-nitroacetophenone; Ethanone, 1-(2,4-dichloro-5-fluoro-3-nitrophenyl)-; 5-Fluoro-2,4-dichloro-3-nitroacetophenone; 3-Nitro-2,4-dichloro-5-fluoroacetophenone; CAS 887267-36-9
EINECS	Contact for details

Quality Control

Our production of 1-(2,4-Dichloro-5-Fluoro-3-Nitrophenyl)Ethanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.