Description

Methyl 3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 887234-98-2 is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a key building block in modern organic synthesis, particularly for cross-coupling reactions. It is essential for research and production in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those requiring the introduction of aryl or heteroaryl groups via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel active ingredients for crop protection products, leveraging its boronate functionality for structural diversification.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its aromatic and functionalizable structure.
• Chemical Synthesis: An essential reagent in academic and industrial R&D laboratories for constructing complex organic molecules, enabling efficient carbon-carbon bond formation.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Item	Details
Product Name	Methyl 3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	887234-98-2
Molecular Formula	C15H21BO4
Molecular Weight	276.14 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylbenzoic acid methyl ester; Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylbenzoate; 3-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Pinacol ester of 2-(Methoxycarbonyl)-6-methylphenylboronic acid; 2-Methoxycarbonyl-6-methylphenylboronic acid pinacol ester; Boronic acid, B-[2-(methoxycarbonyl)-6-methylphenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.