Description

2(3H)-Benzofuranone, 5-Fluoro- is a high-purity fluorinated organic intermediate of significant importance in advanced chemical synthesis. Its core value lies in its precise molecular structure, which serves as a critical building block for the development of complex, high-value molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to introduce the fluoro-benzofuranone moiety to modulate biological activity, solubility, and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Research: Serves as a precursor for the synthesis of specialized fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Organic Light-Emitting Diode (OLED) Materials: Employed in the development of electron-transport or emissive layer materials for display and lighting technologies.
• Fluorescent Probe & Dye Development: Acts as a core structure for creating sensitive fluorophores used in bio-imaging and diagnostic assays.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and fluorination reactions.

Basic Information

Product Name	2(3H)-Benzofuranone, 5-Fluoro-
CAS No.	886985-48-4
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	5-Fluoro-2(3H)-benzofuranone; 5-Fluorophthalide; 5-Fluoro-1-isobenzofuranone; 5-Fluoroisobenzofuran-1(3H)-one; 5-Fluoro-3H-isobenzofuran-1-one; 5-Fluorophthalide; 886985-48-4; 5-Fluoro-1(3H)-isobenzofuranone
EINECS	Contact for details

Quality Control

Our 2(3H)-Benzofuranone, 5-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliable consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential oxidation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.