Description

3,5-Bis(Chloromethyl)-2,4,6-Trifluorobenzotrifluoride is a high-value, multi-functional fluorinated aromatic building block. This compound is critical for introducing the trifluoromethyl and reactive chloromethyl groups into complex molecular architectures, enabling precise chemical modifications. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex drug molecules, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Employed to synthesize specialty fluorinated polymers, coatings, and resins that offer superior chemical resistance, thermal stability, and low surface energy.
• Cross-coupling Reactions: A versatile substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create complex biaryl structures.
• Ligand & Catalyst Development: Useful precursor for synthesizing novel fluorinated ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	3,5-Bis(Chloromethyl)-2,4,6-Trifluorobenzotrifluoride
CAS No.	886762-13-6
Molecular Formula	C9H3Cl2F6
Molecular Weight	311.02 g/mol
Synonyms	2,4,6-Trifluoro-3,5-bis(chloromethyl)benzotrifluoride; 1,3-Bis(chloromethyl)-2,4,6-trifluoro-5-(trifluoromethyl)benzene; α,α,α,3,5-Pentachloro-2,4,6-trifluorotoluene (related); Bis(chloromethyl)trifluorobenzotrifluoride; 886762-13-6; 3,5-Di(chloromethyl)-2,4,6-trifluorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Chloromethyl)-2,4,6-Trifluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.