Description

4-(2-Hydroxypropan-2-Yl)Phenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key synthon for constructing biaryl motifs found in numerous drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or building block for creating organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for methodology development and library synthesis via palladium-catalyzed cross-coupling.
• Ligand Synthesis: Precursor for synthesizing sophisticated ligands used in catalysis and coordination chemistry.
• Sensor Development: Utilized in the creation of molecular sensors and probes due to the boronic acid group's affinity for diols.

Basic Information

Product Name	4-(2-Hydroxypropan-2-Yl)Phenylboronic Acid
CAS No.	886593-45-9
Molecular Formula	C9H13BO3
Molecular Weight	180.01 g/mol
Synonyms	4-(2-Hydroxy-2-propyl)phenylboronic Acid; 2-Methyl-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propan-2-ol (Pinacol ester); 4-(2-Hydroxypropan-2-yl)benzeneboronic Acid; p-(2-Hydroxy-2-propyl)phenylboronic Acid; 4-(1-Hydroxy-1-methylethyl)benzeneboronic Acid; B-[4-(2-Hydroxy-2-propyl)phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 4-(2-Hydroxypropan-2-Yl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.