Description

(4-Fluoro-Phenyl)-Pyrrolidin-3-Yl-Amine CAS NO 886506-05-4 is a high-purity pharmaceutical intermediate featuring a fluorinated phenyl ring linked to an amine-substituted pyrrolidine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by R&D teams in the pharmaceutical and biotechnology sectors for creating potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its fluorinated aromatic and amine functionalities.
• CNS Drug Development: Serves as a precursor for compounds targeting neurological receptors, such as dopamine or serotonin receptors, given its pyrrolidine-amine structure.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and process development.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	(4-Fluoro-Phenyl)-Pyrrolidin-3-Yl-Amine
CAS No.	886506-05-4
Molecular Formula	C10H13FN2
Molecular Weight	180.22 g/mol
Synonyms	3-[(4-Fluorophenyl)amino]pyrrolidine; 1-(4-Fluorophenyl)-3-aminopyrrolidine; 3-Amino-1-(4-fluorophenyl)pyrrolidine; 4-Fluoro-N-(pyrrolidin-3-yl)aniline; Pyrrolidin-3-yl-(4-fluorophenyl)amine; (4-Fluorophenyl)(3-pyrrolidinyl)amine; 886506-05-4; 3-(4-Fluoroanilino)pyrrolidine
EINECS	Contact for details

Quality Control

Our (4-Fluoro-Phenyl)-Pyrrolidin-3-Yl-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.