Description

3'-Chloro-5'-(Trifluoromethoxy)Acetophenone is a high-purity, specialized organic intermediate featuring a unique trifluoromethoxy-substituted aromatic ketone structure. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific halogen and fluorine substituents impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethoxy group for enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organic and organometallic chemistry research to create specialized ligands for catalytic systems.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers and functional materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3'-Chloro-5'-(Trifluoromethoxy)Acetophenone
CAS No.	886503-42-0
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	1-[3-Chloro-5-(trifluoromethoxy)phenyl]ethanone; 3-Chloro-5-(trifluoromethoxy)acetophenone; 1-(3-Chloro-5-(trifluoromethoxy)phenyl)ethan-1-one; 3'-Chloro-5'-trifluoromethoxyacetophenone; 3-Chloro-α,α,α-trifluoro-p-methoxyacetophenone; Acetophenone, 3'-chloro-5'-(trifluoromethoxy)-; Ethanone, 1-[3-chloro-5-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-Chloro-5'-(Trifluoromethoxy)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.