Description

4-Chloro-3-(Trifluoromethylthio)Benzyl Bromide is a high-value, multi-functional halogenated aromatic building block. This compound is prized for its unique combination of reactive sites, making it an essential intermediate for advanced synthesis in demanding research and development. It is primarily sought after by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing complex molecules. Its structure offers versatile pathways for further functionalization, enabling the creation of novel active ingredients and materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethylthio and benzyl bromide groups contribute to efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers for advanced materials with specific electronic or surface properties.
• Custom Synthesis and R&D: A critical reagent for medicinal chemistry and process chemistry teams exploring new chemical entities and optimizing synthetic routes.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethylthio)Benzyl Bromide
CAS No.	886503-38-4
Molecular Formula	C8H5BrClF3S
Molecular Weight	305.54 g/mol
Synonyms	1-(Bromomethyl)-4-chloro-3-[(trifluoromethyl)sulfanyl]benzene; α-Bromo-4-chloro-3-(trifluoromethylthio)toluene; 4-Chloro-3-(trifluoromethylthio)benzyl bromide; (4-Chloro-3-((trifluoromethyl)thio)phenyl)methyl bromide; 4-Chloro-3-(trifluoromethylmercapto)benzyl Bromide; 4-Chloro-3-(trifluoromethylsulfanyl)benzyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-3-(Trifluoromethylthio)Benzyl Bromide is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment supports compliance in cGMP and ISO 9001 environments for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.