Description

2-Dimethylaminomethylidine-6,6,6-Trifluoro-5-Oxohex-3-Enenitrile is a specialized fluorinated organic building block featuring a unique enaminonitrile scaffold. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in fine chemical, pharmaceutical, and life science industries seeking to incorporate trifluoromethyl and reactive nitrile functionalities into target structures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Fluorine Chemistry: An important reagent for introducing fluorine atoms into complex organic molecules, a common strategy in modern drug design to improve metabolic stability and bioavailability.
• Academic & Contract Research: A valuable tool for synthetic organic chemists in universities and CROs (Contract Research Organizations) exploring new reaction methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Dimethylaminomethylidine-6,6,6-Trifluoro-5-Oxohex-3-Enenitrile
CAS No.	886502-60-9
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	6,6,6-Trifluoro-5-oxo-2-[(dimethylamino)methylidene]hex-3-enenitrile; 2-[(Dimethylamino)methylene]-6,6,6-trifluoro-5-oxo-3-hexenenitrile; (E)-2-(Dimethylaminomethylene)-6,6,6-trifluoro-5-oxohex-3-enenitrile; 2-Dimethylaminomethylene-6,6,6-trifluoro-5-oxohex-3-enenitrile; Trifluoromethyl Enaminonitrile Derivative; CAS 886502-60-9
EINECS	Contact for details

Quality Control

Our 2-Dimethylaminomethylidine-6,6,6-Trifluoro-5-Oxohex-3-Enenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.